Dr. Thomas P. Habif, MD discusses Acne Treatment with Topical Retinoids Retin-A. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Topical retinoids are the foundation for the treatment of acne. They are effective for comedonal and inflammatory acne. Mechanism of action Retinoids normalize keratinization. They increase the turnover of follicular epithelial cells, corneocytes are shed at an accelerated rate and comedones are extruded. New comedone formation
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